I-Raman ye-intanethi inquma ngokukhawuleza ukuhambelana kweebhetshi ezininzi zemixube kunye nefom ye-crystalline yezithako ezisebenzayo zamachiza.
Ukubeka iliso kwi-Intanethi kunika iziphumo ezikhawulezayo zokuvavanya ikristale ekujoliswe kuyo, idatha eqhubekayo ikhuthaza iindlela zokusabela kunye neendawo zokugqibela, ukubonelela ngokulungiswa, izikhokelo.
Iintlobo zekristale ezahlukeneyo zechiza elifanayo zingabonisa ukungafani okuphawulekayo kwimbonakalo, ukunyibilika, indawo yokunyibilika, izinga lokuchithwa, i-bioavailability, njl.Ngoko ke, kuyimfuneko ukuqinisekisa ubukho befom ye-crystal ekujoliswe kuyo ngexesha lokwenziwa kweziyobisi kunye neenkqubo zokuqulunqa.
Kwinkqubo yokuphuhlisa ichiza elitsha, kuyimfuneko ukubeka iliso ngexesha lokwenyani ukubunjwa kwesigaba sekristale seyeza kwisisombululo sempendulo ye-synthesis.Oku kwenzelwa ukwandisa inkqubo kunye nokuqinisekisa ukuba inqanaba lekristale ekujoliswe kulo ichiza liyadityaniswa.I-Raman spectroscopy ingasetyenziselwa ukubeka iliso kwi-i-situ, ukubonelela uhlalutyo lwexesha langempela lokubunjwa kwesigaba se-crystalline kwi-reaction synthesis ye-chiza, ngokukodwa ilungele uhlalutyo olubanzi lwe-polymorphic kunye ne-amorphous API-containing systems.
I-Online Raman spectroscopy yenza lula uhlolo lwesigaba sekristale kwiimeko zokusabela ezahlukeneyo, njengoko kubonisiwe luvavanyo lweebhetshi zenkampani yoxubo lweyeza.Iziphumo ziqinisekisile ulungelelwaniso kunye nesithako esisebenzayo samayeza, esibonisa uphando oluyimpumelelo.Unyino lwangaphambili kusetyenziswa i-XRD kunye nezinye izixhobo zaselebhu kukhokelele kwimithintelo yedatha kunye nemijikelo yophuhliso eyandisiweyo.Elinye ityala libonise ulwahlulo oluyimpumelelo lwexesha langempela lokuguqulwa kwesigaba se-crystal kwiinkqubo ezintandathu ezahlukeneyo, ukubonelela ngokukhawuleza kwiziphumo zemveliso.
I-Online Raman imisela ngokukhawuleza iziphumo zenguqu yesigaba sekristale phantsi kweemeko ezahlukeneyo zokusabela.
Ixesha lokuposa: Dec-26-2023